For people who would like to learn more about our research, but don't want to deal with the umm filled long video, there is an article which is basically a transcript of a talk I gave at the royal society in london last year at http://depts.washington.edu/bakerpg/: click on "publications" and then on "2006"; it is called "Prediction and design of macromolecular structures and interactions"
We have shortened the deadline for workunits from two weeks to one week, to keep up with the tight CASP7 schedule. We will increase the deadline back to two weeks at the end of the summer, after CASP7.
I wrote an internal benchmark for Rosetta last week, and Rom now has a version that uses this to compute credits. Rom suggests however that we wait until after CASP to deploy it because it may take a few iterations to make it acceptable to everybody. I don't know how difficult it will be to "get it right", but I'd like to start testing it on Ralph soon.
We made submissions for the first two that were due yesterday (targets 284 and 287). if you have 287 work units still remaining on your computer you can delete them. Please keep all others running!
CASP7 is turning out to be an even more extensive test of rosetta@home than we expected! A much larger fraction of the proteins than we expected based on previous CASPS are both relatively small and completely unrelated to any protein of known structure. These targets are perfect for the methodology we have been developing at rosetta@home since last september when the project began. Things are exciting now, but imagine what it will be like in a couple of months when the true structures are released and rosetta developers, rosetta@home participants, and the whole world can see how good (hopefully!) the predictions are.
Welcome to all of our new participants! I have only very sporadic internet access as I'm out of town this next week, but I look forward to interacting with all of you here when I return. I was absolutely delighted to see the large increases of the last few days; they will really help accomplish the goals of the project! Thanks again to all of you, David.
We have updated rosetta apps to version 5.22. This version has some new debugging features as well as the support for Intel Mac platform. Please read details here.
1. We have put in a symbol store to give us more debugging
information. We'll only get this information back, though, if you
have the latest BOINC release, available here. If you have the time, please download it!
This will be our number one debugging tool.
2. Apps that can't find the appropriate libraries to display graphics
(for whatever reason) will now not display graphics. Hopefully, this
will help with some of the rare cases where graphics is triggering
3. We removed the excessive print statements to stdout.txt that were
filling up some users's disks for a particular kind of workunit.
4. We we made some fixes to the graphics, like removing the ghost
"Accepted Energy" and making sure all protein pictures are properly
5. There have been some fixes to clean up how different threads (e.g.
rosetta itself, graphics, the watchdog) shut down at the end of the
run. We expect this to reduce errors.
6. A version for Mac Intel machines has been released!