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发表于 2019-3-13 23:49:01
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2019-03-08: Rosetta@Home, IPD's first nanoparticle vaccine
Researchers in the King lab, an affiliate of the Institute for Protein Design, published a report in Cell describing a computer-designed nanoparticle vaccine targeting respiratory syncytial virus (RSV). Although Rosetta@home was not directly used for this study, Rosetta@home volunteers provided computing for related research and development.
From IPD news:
Millions of children will visit hospitals this year, sickened by RSV. Infection is usually mild, causing only fevers, runny noses and frightened parents. But, in severe cases, barking coughs and painful wheezing can indicate serious respiratory complications, including bronchiolitis and pneumonia.
RSV is the primary cause of pneumonia in children under one and is therefore the leading cause of infant mortality worldwide after malaria. Although virtually every child on Earth will get RSV before the age of three, an estimated 99 percent of RSV deaths occur in developing countries. Despite substantial effort, there is not yet a safe and effective vaccine.
Today, an international team of scientists co-led by researchers at the IPD report in Cell a first-of-its-kind vaccine candidate for RSV. It elicits broadly neutralizing antibodies against respiratory syncytial virus in mice and monkeys, paving the way for human clinical trials.
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2019-03-08: Rosetta@Home, 蹭一波热点
King lab (Institute for Protein Design 的分支机构)的研究人员发表了一份报告,报告中描述了一种计算机设计的、针对呼吸道合胞病毒(RSV)的纳米微粒疫苗。虽然Rosetta@home没有在这项研究中起到直接作用,但是Rosetta@home的志愿者们为相关的研究和开发贡献了计算能力。

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