[BOINC] [生命科学类] Rosetta@home

gengli00

June 25, 2008
The rosetta application has been updated to version 5.98. This version includes a bug fix for the stalled client issue. Please report problems in this thread.
rosetta计算程序以更新至5.98版,此版修复了一个BUG

Tynox

Aug 5, 2008
The minirosetta application has been updated to version 1.32. Release information is available in this post. Please report problems in this thread.

The recent down time was due to our fileservers crashing. We are still looking into the cause.

Sept 8, 2008
The Italian translation of this site is now available thanks to Manuel L, Drake VC, boboviz, Venturini D, and Ducati 749 of the BOINC.Italy team.

Sept 14, 2008
We are currently participating to the first competition for modeling the structure of an important biological receptor. This protein is much larger than all the targets submitted so far and the calculation should last around 3 hours per model on a normal machine. The jobs start with 'AA2A.' If you have a short run time preference and you notice these jobs running past it, please do not abort them.

Oct 18, 2008
We're having increasing problems with our project's fileserver, causing intermittent outages. We're in the process of building out the replacement system but it is going to take some time to iron out the issues. We apologize for the troubles.

October 28, 2008
The minirosetta application has been updated to version 1.39. In this version, we added two important applications to minirosetta, docking and protein folding with explicit zinc metal ion. New features have been added to the graphic to show chain colors for a multi-chain protein complex and display metal ions by sphere. Please report problems in this thread. Thanks.

November 6, 2008
The minirosetta application has been updated to version 1.40. This version contains improved protein-protein docking along with small-molecule ligands and the capabilities to do design, where the surface amino-acid residues are allowed to mutate during the simulation. Messages on the scientific aspects will be posted on the message board. Please report problems in this thread

November 14, 2008
Our fileserver crashed last night. We are planning to upgrade the system very soon. Sorry for any inconvenience.

November 14, 2008
Outage Notice: the project will be down for maintenance starting at 2:00 PST today.

On an unrelated note: WE ARE PLANNING TO INCREASE THE DEFAULT RUN TIME TO 6 HOURS AND THE MINIMUM TO 3 TO REDUCE THE LOAD ON OUR SERVERS. When and how this will occur has not yet been decided. If you have any concerns or would like to add to the discussion please post to this thread.

November 30, 2008
Unplannded Outage: the project was down today while the service was migrated to our new SAN. Sorry for the inconvenience. For more details, see technical news. -KEL


December 1, 2008
Rosetta@home is today's featured article on Wikipedia. We'd like to thank all the contributors that made this possible and those that have made the Wikipedia article such a wonderful resource.

We'd also like to welcome all the new users that have discovered Rosetta@home through the featured article.

Tynox

January 6, 2008/正确的发布时间应该是:January 6,2009
Our database server lost power accidentally as work was being done on the rack. We are back up and running now.

January 6, 2008/正确的发布时间应该是:January 6,2009
Well today has not been a good day for R@h. The external interface for our download/upload servers and the Ralph@home project is currently down. We will not be able to fix this until early tomorrow. Sorry for any inconvenience. Looks like it's going to be a busy day for our servers tomorrow.
为周二服务器的意外停机道歉.


January 6, 2008/正确的发布时间应该是:January 6,2009
The problem has been fixed. Sorry it took so long - I was already heading for home before the problems began. For more details - a novel problem indeed - see technical news. -KEL

他们也发现这个囧问题了...今天更新的三条新闻日期居然都写着2008
[或许我应该把时间校正...]

[ 本帖最后由 Tynox 于 2009-1-10 10:51 编辑 ]

Tynox

January 26, 2009
The minirosetta application has been updated to version 1.54. For details and to report bugs, go to this thread. This update is a major bugfix update addressing many issues brought forward by users over the last months. Your feedback is highly appreciated!

minirosetta计算程序升级到v1.54,主要是对一些BUG的修复.

[ 本帖最后由 Tynox 于 2009-2-2 10:58 编辑 ]

zglloo

February 16, 2009
A fileserver/SAN hiccup caused the entire project to pause for a number of hours. Sorry for the outage. -KEL

因为一些文件存贮服务器的故障原因（可能是存储满了）而暂时停止数个小时

[ 本帖最后由 zglloo 于 2009-2-16 02:01 编辑 ]

Tynox

February 18, 2009
Our server's back up, minirosetta 1.54 is proving to be rather stable and we got 2.5M workunits lined up - come and get them while they're fresh!
服务器恢复.minirosetta 1.54计算程序被证明是稳定可靠的.目前有超过250万的任务包,各位速度去抢...

February 25, 2009
Outage Notice: the project will be down for maintenance starting at 2:00 PST today. We will be upgrading the database server which may take a few hours.
停电通知:项目服务器将会在今天2:00 PST下线进行维护.我们会花一些时间来升级数据服务器.

February 26, 2009
We're back online with a brand new database server !
新数据服务器上线!

March 2, 2009
Outage Notice: the project will be down again for maintenance starting at 2:00 PST today. It may take a few hours.
抱歉,今天服务器会有几小时的停机维护.

March 2, 2009
We're up and running again. Sorry for the extended downtime. We ran into some issues while trying to tune the new database server. -DK
服务器恢复运行.

March 11, 2009
Take a look at the recent work you've made possible with your contributions! D. Baker discusses the six (6!) manuscripts that the group is publishing, having used the computing power-house that is R@H, in the Rosetta@home Journal.

[ 本帖最后由 Tynox 于 2009-3-27 18:29 编辑 ]

Youth

Our project received a large donation from an anonymous donor and following the donor's suggestion, the University of Washington created a special Rosetta@home fund which makes it easy to make a tax deductible donation directly to our project. We've added a link to more information on our homepage in the "Join Rosetta@home" navigation section. Also, for more information see David Baker's recent journal post.


项目刚收到一批数额很大的匿名捐赠！！！根据捐赠者的建议，华盛顿大学创建了一个Rosetta@home基金，以方便以后对我们项目的免税捐赠。更详细的情况我们放在了首页上的“加入Rosetta@home”部分。另外，也可以看项目论坛中的相关主题：http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#60267

Tynox

April 28, 2009
We had a brief hiccup today with our filesystem which brought the project down for a few hours. The redundancy in the Polyserve file server system that handles our BOINC data failed during a routine maintenance window. No outage was expected, and it took a long time to get the multiple servers communicating again.
||28号文件服务器当机了几小时.

April 29, 2009
The minirosetta application has been updated to version 1.64. For details and to report bugs, go to this thread.
||minirosetta计算程序升级到1.64版本.

Youth

We just found a source of flu surface protein closely related to that on the strain making headlines in the last few days, and are starting to design tight binding inhibitors that target a site where the flu virus can't change. We will keep you posted as these design work units are sent out on rosetta@home. Fortunately, it seems that there may have been a bit of a false alarm with the flu in this case, but it is a good test case for us as we ultimately aim, with your help, to be able to design blockers to new pathogens within a relatively short time.

和甲型h1n1流感相关的，哪位业内人士准确翻译一下？

zglloo

这条新闻 那里看到的？
怎么没有看到这个 新闻刊登！

[ 本帖最后由 zglloo 于 2009-5-4 19:02 编辑 ]

Julian_Yuen

水平有限，尽力翻译了一下，不很通顺，也不知道意思对不对
--------------------------------------------------------------------------------------------
我们刚刚发现了与前一段时间歪曲（了事实）的（新闻）头条（译注：不知这里是否是指猪流感被更名为甲型H1N1等情况）所报道的流感（病毒）相接近的流感（病毒）的表面抗原的来源，并开始把流感病毒不发生改变的位置做为目标（靶子）来设计紧束缚抑止物。当针对这个来设计的WU通过Rosetta@home进行发放的时候，我们将会向大家进行通告。幸运的是，虽然该方法在当前情况下对流感病毒还有些误报，但是对我们来说，借用你们的帮助来进行极限测试、并在短期内设计出对新病原体的阻断药，是一种很好的试验方式。

Youth

官方论坛里的帖子，DM同学不定期更新：）

Tynox

May 19, 2009
Outage Notice: the project will be down for maintenance starting at around 11:00AM PST tomorrow the 20th. It may take a few hours. We will be replacing some memory for our database server and doing a full backup of the database.
5月19日:服务器维护.将会持续几个小时.为数据服务器更换内存,再则是备份数据.

May 26, 2009
The minirosetta application has been updated to version 1.71. For details and to report bugs, go to this thread.
5月26日:minirosetta计算程序升级到1.71.详细信息和bug报告请点击链接.

June 12, 2009
The minirosetta application has been updated to version 1.75. For details and to report bugs, go to this thread.
minirosetta计算程序升级到1.75.更多信息和BUG报告请点击链接.

June 16, 2009
The minirosetta application has been updated to version 1.76. For details and to report bugs, go to this thread.
minirosetta计算程序已经升级到1.76.更多细节及Bug报告请点击链接.

June 22, 2009
The minirosetta application has been updated to version 1.80. For details and to report bugs, go to this thread.
minirosetta计算程序升级到1.80.更多细节及Bug报告请点击链接.

July 14, 2009
The minirosetta application has been updated to version 1.82. For details and to report bugs, go to this thread.
minirosetta计算程序升级到1.82.更多细节及Bug报告请点击链接.

July 16, 2009
The minirosetta application has been updated to version 1.86. For details and to report bugs, go to this thread.
minirosetta计算程序升级到1.86.更多细节及Bug报告请点击链接.

July 16, 2009
We've had a problem with the signatures on the 1.86 update. This issue should hopefully be resolved now with 1.87. Sorry about the outage.
在1.86的重要升级中我们遇到了一些问题.这个问题将在1.87中解决.对此感觉十分抱歉.

July 29, 2009
Due to a massive slowing down of the lastest code, we reverted the application back to a version equivalent to 1.82, while we work on the code. Sorry about the outage.
因为最近一次代码的严重放缓(这里怎么翻译好?),我们把计算程序返回到1.82.对这次事故表示抱歉.


July 30, 2009
We have identify the bug that causes the program to slow down. We're currently working on updating the client. This should also solved the instant quitting problem in the last 1-2 days.
我们已经去任该Bug会导致程序计算变慢.我们正在升级客户端.这应该也会解决在过去一两天服务器离线的问题.[我猜就是这个问题了]

July 30, 2009
The minirosetta application has been updated to version 1.90. For details and to report bugs, go to this thread.
minirosetta计算程序升级到1.90.更多细节及Bug报告请点击链接.

July 30, 2009
A few details on what was done to fix the problems in the last few days are posted here.
一些在过去几天解决问题的细节请点击链接查看.

July 30, 2009
The project will be offline for a bit as we work on adding a couple web servers to the mix to help reduce the load on our servers.
当我们增加一些服务器到群组时项目会下线一段时间.

[ 本帖最后由 Tynox 于 2009-7-31 08:07 编辑 ]

feynord

楼上手好快~
建议每次更新都发一个新回复，这样能顶一下。

Tynox

一般都是下面有人顶后我才使用新回复.
或者就是一回复内容太多了再进行更新.
使用了RSS而且现在时间充裕,一看到RSS更新了马上就到这里更新.