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本帖最后由 金鹏 于 2013-4-13 16:57 编辑
new bigbeta project 8103
by kasson » Fri Feb 15, 2013 3:27 am
We're releasing a new bigWU project to beta, 8103. This is essentially a clone of 8102 (based on what we're seeing in 8102, we've identified some more conditions to explore) and thus has identical points & deadlines.
The projects in our 810X series have to do with how influenza virus gets into cells. This is something we do a lot of work on, both because influenza is an important disease and because the process of cell entry by influenza virus is a model to study other viruses as well as things like nerve impulse transmission. Thus the most direct applications are to infectious disease, but we hope to address diseases such as Alzheimer's (where some of the drugs specifically target certain kinds of nerve impulse transmission). There has been a lot of exciting experimental work in this field to come out recently, and our experimental colleagues are encouraging us to do more simulations. Unfortunately, the simulations take time (and we need a lot of simulations). That's where you come in...thanks to the consistent help of bigWU donors over time, we are starting to see some interesting results. We're following those up and hope they pan out.
Thanks for testing! New beta project 8530-85XX
by Per » Tue Nov 06, 2012 12:49 am
We are releasing a new (A3) project series for our influenza research. Please find data below:
8530: Base points 1668, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8531: Base points 1664, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8532: Base points 1670, Deadline 13.4, k-factor 3.01, Preferred deadline 8.1
8533: Base points 1681, Deadline 13.5, k-factor 3.00, Preferred deadline 8.1
8534: Base points 1674, Deadline 13.5, k-factor 2.99, Preferred deadline 8.1
8535: Base points 1689, Deadline 13.6, k-factor 2.99, Preferred deadline 8.2
8536: Base points 1674, Deadline 13.5, k-factor 2.99, Preferred deadline 8.1
8537: Base points 1668, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8538: Base points 1670, Deadline 13.4, k-factor 3.00, Preferred deadline 8.1
8539: Base points 1689, Deadline 13.6, k-factor 2.99, Preferred deadline 8.2
8540: Base points 1673, Deadline 13.4, k-factor 3.01, Preferred deadline 8.1
8541: Base points 1654, Deadline 13.3, k-factor 3.00, Preferred deadline 8.0
8542: Base points 1668, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8543: Base points 1657, Deadline 13.3, k-factor 3.01, Preferred deadline 8.0
8544: Base points 1673, Deadline 13.4, k-factor 3.01, Preferred deadline 8.1
8545: Base points 1668, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8546: Base points 1665, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
8547: Base points 1689, Deadline 13.6, k-factor 2.99, Preferred deadline 8.2
8548: Base points 1690, Deadline 13.6, k-factor 3.00, Preferred deadline 8.2
8549: Base points 1668, Deadline 13.4, k-factor 3.00, Preferred deadline 8.0
Please report any problems!
Thanks
/Per
Project description:
Influenza is both a seasonal illness and a periodic worldwide pandemic disease, responsible for approximately 500000 deaths per year. The influenza virus infects cells via a process of membrane fusion between the viral envelope and cellular endosomal membranes; this is mediated by the influenza hemagglutinin protein. Elucidating the mechanisms common to all membrane fusion events is of great importance.
In these projects, we want to understand the process by which the fusion peptide inserts into the membrane and changes conformation. There is some controversy over how the peptide inserts and what shapes it refolds to inside the membrane. We are comparing to experimental data from our collaborators.
We hope to continue to shed light on the influenza fusion process, getting an atomic level understanding of why and how it happens.
加了bigbeta参数后8103今日接到，是和8102一样甜蜜蜜，
SMP接到过8533 8530 8557 ......
另外显卡加了BETATEAM参数接到7660毒包，7698还木有接到
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发表于 2013-2-17 20:57:19
发表于 2013-2-19 14:13:30
