[独立平台] [生命科学类] Folding@Home
- 1# vmzy
- 2703676952005-7-23 21:56:28
7/15/2005
A cautionary note about Advanced methods, QMD, and big WUs.
There have been some questions about the use of flags and FAH's stability and I wanted to make an announcement to try to clear things up.
There are two flags in particular which are to be used with caution. The big WU flag gets big WUs, but these big WUs may be poorly suited for older machines. The bigWU flag combined with advanced methods brings big WUs that are more advanced (QMD"s right now).
Gromacs was originally released as an advanced only WU until we could work things out to make it more stable. By having a flag, one would have to opt in and the default (Tinker in that case) would be stable.
We've kept that philosophy throughout FAH. Right now, Gromacs is stable, but QMD is much less so. QMD is also a big WU, so one has to choose both QMD and advanced methods to get it. BigWU + adv gets highly experimental QMD WUs and they may not work well for all. We suggest that one only use both flags if you're absolutely sure this is what you want (if you're not sure what you want, I would suggest that you don't want QMD's).
We should have been more clear about this, but hopefully this post will help. Due to this confusion, I'm going to suspend QMD's until we can be sure that a significant number of people have gotten the word on this.
So, as a summary, advanced methods is just that -- something which may bring more points, but also more trouble. Please consider this tradeoff when you choose settings.
2005年7月15日
关于advanced methods,QMD,和大WU的说明。
如今有很多关于参数的用途和FAH稳定性的一些疑问，我想就此说明一下，以澄清此事。
有两种参数要特别小心使用。下载大WUs的bigWU参数,这些大WUs并不适用于慢机器。使用advanced methods和bigWU参数下载的大WUs(现在是QMD)更是如此。
Gromacs最初是作为仅供快机器使用而发布的，直到我们能使它更加稳定的工作时才会完全开放。只有选中大WU选项才会打开BigWU参数,而默认参数(Tinker)很稳定。
我们冷静下来看FAH。现在,Gromacs是稳定的,但QMD却不。QMD也是大WU, 你必须同时打开QMD和advanced methods参数才能下载它。BigWU+adv会下载实验性的QMD WUs，并且他们现今运作还不太稳定。我们建议您没有必要不要同时使用这两个参数(如果您不是非要下载,我会建议您不要下载QMD) 。
我们应该对此更加明白,但原这个声明有帮助。由于这混乱,我将暂停QMD直到我们能肯定大多数人看到了这篇文章。
就这些了,总之,advanced methods就是--也许会带来更多积分,但也会带来更多麻烦。当您设置参数时请慎重考虑一下这样是否划算。
A cautionary note about Advanced methods, QMD, and big WUs.
There have been some questions about the use of flags and FAH's stability and I wanted to make an announcement to try to clear things up.
There are two flags in particular which are to be used with caution. The big WU flag gets big WUs, but these big WUs may be poorly suited for older machines. The bigWU flag combined with advanced methods brings big WUs that are more advanced (QMD"s right now).
Gromacs was originally released as an advanced only WU until we could work things out to make it more stable. By having a flag, one would have to opt in and the default (Tinker in that case) would be stable.
We've kept that philosophy throughout FAH. Right now, Gromacs is stable, but QMD is much less so. QMD is also a big WU, so one has to choose both QMD and advanced methods to get it. BigWU + adv gets highly experimental QMD WUs and they may not work well for all. We suggest that one only use both flags if you're absolutely sure this is what you want (if you're not sure what you want, I would suggest that you don't want QMD's).
We should have been more clear about this, but hopefully this post will help. Due to this confusion, I'm going to suspend QMD's until we can be sure that a significant number of people have gotten the word on this.
So, as a summary, advanced methods is just that -- something which may bring more points, but also more trouble. Please consider this tradeoff when you choose settings.
2005年7月15日
关于advanced methods,QMD,和大WU的说明。
如今有很多关于参数的用途和FAH稳定性的一些疑问，我想就此说明一下，以澄清此事。
有两种参数要特别小心使用。下载大WUs的bigWU参数,这些大WUs并不适用于慢机器。使用advanced methods和bigWU参数下载的大WUs(现在是QMD)更是如此。
Gromacs最初是作为仅供快机器使用而发布的，直到我们能使它更加稳定的工作时才会完全开放。只有选中大WU选项才会打开BigWU参数,而默认参数(Tinker)很稳定。
我们冷静下来看FAH。现在,Gromacs是稳定的,但QMD却不。QMD也是大WU, 你必须同时打开QMD和advanced methods参数才能下载它。BigWU+adv会下载实验性的QMD WUs，并且他们现今运作还不太稳定。我们建议您没有必要不要同时使用这两个参数(如果您不是非要下载,我会建议您不要下载QMD) 。
我们应该对此更加明白,但原这个声明有帮助。由于这混乱,我将暂停QMD直到我们能肯定大多数人看到了这篇文章。
就这些了,总之,advanced methods就是--也许会带来更多积分,但也会带来更多麻烦。当您设置参数时请慎重考虑一下这样是否划算。
评分
- 2# vmzy
- 2005-7-23 21:57:46
7/17/2005
Plan for QMD rollout and new client mod
Our plan is to re-release QMD WUs starting on Monday around noon PST. Hopefully enough people will have heard about the various issues. We will release them gradually, starting with a high memory limit. The previous memory limit was set to 500MB. We'll start conservatively with a limit of 1000MB and then gradually work down from there. Note that in the current client, the memory reported to the AS is the total memory of the box. For SMP boxes, all clients will report the same amount of RAM, which is bad since they are in fact all sharing that RAM. Thus, we will re-release these with a large RAM request to try to help this issue.
In addition to this re-release plan, we are working to release a new v5 client rev which allows the donor to set the amount of RAM reported to the AS. Thus, if your dual has 1GB and you are running 2 clients, you can choose to report to the AS that each client should only use 500MB. One can also use this to simply request smaller WUs on machines. This is a "soft limit" as there is no code to ensure that the core sticks to this, but this soft request will still go a long way to allocating WUs correctly to machines. We are also considering the possibility of a hard limit, which would stop cores from using more memory than allocated. It is unclear whether this is a good idea (and how to do this right) and we will do more testing on this before we release this feature in v6.
2005年7月17日
QMD重新发放和新客户修改计划
我们计划在星期一中午左右(PST)开始重新发放QMD WUs。希望有足够多的人看到了全部的问题公告。我们即将重新发放他们,刚开始会有极高的内存限制。早先内存限制为500MB。从现在开始我们保守地将设为1GB内存限制，然后将逐渐的降低限制。注意,在当前的客户中,向AS报告的内存容量是机子的总内存量。对SMP机器而言,所有客户端将报告同样的RAM容量,这样不好因为实际上他们是分享所有的RAM。因而, 我们将发布一个带有大内存需求参数的新内核以求设法帮助解决这个问题。
除了这个重新发布计划之外,我们正在准备发布一个允许志愿者设置向AS报告的RAM容量的新v5客户端。因而, 如果您的双核系统有1GB内存并且同时运行2个客户端,您能选择向AS报告各个客户只拥有500MB内存。这样你可以请求到较小的WUs。这是"软件限制"尽管没有代码验证其数值的准确性,但这个软件需求限制在相当长的一段时间内将给大部分机器正确地分配WUs。并且我们也在考虑加入硬件限制,这会有效的防止内核使用内存量超限。现在还不清楚这是否是一个好想法(并且我们不知道究竟怎么做才好)，在v6发布前我们将对此功能做更多的测试。
Plan for QMD rollout and new client mod
Our plan is to re-release QMD WUs starting on Monday around noon PST. Hopefully enough people will have heard about the various issues. We will release them gradually, starting with a high memory limit. The previous memory limit was set to 500MB. We'll start conservatively with a limit of 1000MB and then gradually work down from there. Note that in the current client, the memory reported to the AS is the total memory of the box. For SMP boxes, all clients will report the same amount of RAM, which is bad since they are in fact all sharing that RAM. Thus, we will re-release these with a large RAM request to try to help this issue.
In addition to this re-release plan, we are working to release a new v5 client rev which allows the donor to set the amount of RAM reported to the AS. Thus, if your dual has 1GB and you are running 2 clients, you can choose to report to the AS that each client should only use 500MB. One can also use this to simply request smaller WUs on machines. This is a "soft limit" as there is no code to ensure that the core sticks to this, but this soft request will still go a long way to allocating WUs correctly to machines. We are also considering the possibility of a hard limit, which would stop cores from using more memory than allocated. It is unclear whether this is a good idea (and how to do this right) and we will do more testing on this before we release this feature in v6.
2005年7月17日
QMD重新发放和新客户修改计划
我们计划在星期一中午左右(PST)开始重新发放QMD WUs。希望有足够多的人看到了全部的问题公告。我们即将重新发放他们,刚开始会有极高的内存限制。早先内存限制为500MB。从现在开始我们保守地将设为1GB内存限制，然后将逐渐的降低限制。注意,在当前的客户中,向AS报告的内存容量是机子的总内存量。对SMP机器而言,所有客户端将报告同样的RAM容量,这样不好因为实际上他们是分享所有的RAM。因而, 我们将发布一个带有大内存需求参数的新内核以求设法帮助解决这个问题。
除了这个重新发布计划之外,我们正在准备发布一个允许志愿者设置向AS报告的RAM容量的新v5客户端。因而, 如果您的双核系统有1GB内存并且同时运行2个客户端,您能选择向AS报告各个客户只拥有500MB内存。这样你可以请求到较小的WUs。这是"软件限制"尽管没有代码验证其数值的准确性,但这个软件需求限制在相当长的一段时间内将给大部分机器正确地分配WUs。并且我们也在考虑加入硬件限制,这会有效的防止内核使用内存量超限。现在还不清楚这是否是一个好想法(并且我们不知道究竟怎么做才好)，在v6发布前我们将对此功能做更多的测试。
评分
- 3# vmzy
- 2005-7-23 21:59:04
7/18/2005
QMD re-relase commenced
We have re-released the QMD's, but with a higher memory restriction. Your machines will have to have 1GB of RAM in order to receive these WUs. We will lower this RAM requirement in the new future, but we want to start conservatively.
2005年7月18日
QMD重新发放开始
我们重新发放了QMD,但有一个很高的内存限制。为了下载这些WUs，您的机器必须有1GB内存。在未来，我们将逐渐降低这个RAM需求,但我们想要保守地开始。
7/18/2005
Proxy bug fixed
Adam has fixed a proxy bug recently reported and we are now testing this fix gradually. First the port 80 AS and certain work servers, then the main AS. So far, everything seems ok on our end, but it will take more of a complete roll out for donors to see a difference.
2005年7月18日
代理漏洞修正
Adam修正了最近被报告代理漏洞，我们现在正在逐渐测试这个修正。首先80端口AS和某些工作服务器,然后是全部AS。到目前为止,我们看来一切似乎正常,但它需要很多的志愿者参与才可能看出区别。
QMD re-relase commenced
We have re-released the QMD's, but with a higher memory restriction. Your machines will have to have 1GB of RAM in order to receive these WUs. We will lower this RAM requirement in the new future, but we want to start conservatively.
2005年7月18日
QMD重新发放开始
我们重新发放了QMD,但有一个很高的内存限制。为了下载这些WUs，您的机器必须有1GB内存。在未来，我们将逐渐降低这个RAM需求,但我们想要保守地开始。
7/18/2005
Proxy bug fixed
Adam has fixed a proxy bug recently reported and we are now testing this fix gradually. First the port 80 AS and certain work servers, then the main AS. So far, everything seems ok on our end, but it will take more of a complete roll out for donors to see a difference.
2005年7月18日
代理漏洞修正
Adam修正了最近被报告代理漏洞，我们现在正在逐渐测试这个修正。首先80端口AS和某些工作服务器,然后是全部AS。到目前为止,我们看来一切似乎正常,但它需要很多的志愿者参与才可能看出区别。
评分
- 4# vmzy
- 2005-7-23 22:01:50
7/19/2005
QMD re-release update
QMD's are now going to machines reporting 900MB or more and with the appropriate flags (BigWU + advmethods).
2005年7月19日
QMD重新发放相关信息更新
QMD下载限制改为900MB以上内存＋特定参数(BigWU+advmethods)。
7/21/2005 QMD re-release update
QMD's are now going to machines reporting 750MB or more and with the appropriate flags (BigWU + advmethods).
2005年7月21日
QMD重新发放相关信息更新
QMD下载限制改为750MB以上内存＋特定参数(BigWU+advmethods)。
QMD re-release update
QMD's are now going to machines reporting 900MB or more and with the appropriate flags (BigWU + advmethods).
2005年7月19日
QMD重新发放相关信息更新
QMD下载限制改为900MB以上内存＋特定参数(BigWU+advmethods)。
7/21/2005 QMD re-release update
QMD's are now going to machines reporting 750MB or more and with the appropriate flags (BigWU + advmethods).
2005年7月21日
QMD重新发放相关信息更新
QMD下载限制改为750MB以上内存＋特定参数(BigWU+advmethods)。
评分
- 5# vmzy
- 2005-8-2 23:31:44
7/23/2005
QMD re-release update
QMD's are now going to machines reporting 600MB or more and with the appropriate flags (BigWU + advmethods). We're almost done with the rollout and should be back to the previous value (504MB) on Tuesday.
2005年7月23日
QMD重新发放相关信息更新
QMD下载限制改为600MB以上内存＋特定参数(BigWU+advmethods)。我们已经几乎完成了测试，星期二我们会把内存需求调回初始值(504MB)。
QMD re-release update
QMD's are now going to machines reporting 600MB or more and with the appropriate flags (BigWU + advmethods). We're almost done with the rollout and should be back to the previous value (504MB) on Tuesday.
2005年7月23日
QMD重新发放相关信息更新
QMD下载限制改为600MB以上内存＋特定参数(BigWU+advmethods)。我们已经几乎完成了测试，星期二我们会把内存需求调回初始值(504MB)。
评分
- 6# vmzy
- 2005-8-2 23:32:12
7/25/2005
QMD re-release complete
QMD's are now going to machines reporting 504MB or more and with the appropriate flags (BigWU + advmethods). We're now back to the previous value.
2005年7月25日
QMD重新发放工作结束
QMD下载限制改为504MB以上内存＋特定参数(BigWU+advmethods)。我们现在使用初始值.
7/25/2005
New Assignment Server (AS) fallback scheme.
We've implemented a new AS fallback scheme for how WUs are assigned. We will talk more about about how this works once we see if it works well. It's now being tested on both ASes.
2005年7月25日
新任务服务器(AS)更换计划。
我们制定了一套用于分配WUs的新AS的更换计划。如果这有效的话我们将讨论更多关于其工作原理的话题。它现在在两台AS上测试。
7/25/2005
Client v5.04 public beta release
Client v.5.04 is in public beta for Linux and Windows (console). It allows configuration of the amount of memory reported and the setting of advmethods through the Configuration so that it persists. This is a maintenance release, with more signficant improvements coming in v.6. See http://folding.stanford.edu/beta for more details.
2005年7月25日
v5.04公测版客户端发布
v.5.04 Linux和Windows(命令行)公厕版客户端发布。它允许通过Configuration选项设定内存报告数量和设置advmethods参数。这是测试版,带有v.6版中的一些改善功能。详见http://folding.stanford.edu/beta。
QMD re-release complete
QMD's are now going to machines reporting 504MB or more and with the appropriate flags (BigWU + advmethods). We're now back to the previous value.
2005年7月25日
QMD重新发放工作结束
QMD下载限制改为504MB以上内存＋特定参数(BigWU+advmethods)。我们现在使用初始值.
7/25/2005
New Assignment Server (AS) fallback scheme.
We've implemented a new AS fallback scheme for how WUs are assigned. We will talk more about about how this works once we see if it works well. It's now being tested on both ASes.
2005年7月25日
新任务服务器(AS)更换计划。
我们制定了一套用于分配WUs的新AS的更换计划。如果这有效的话我们将讨论更多关于其工作原理的话题。它现在在两台AS上测试。
7/25/2005
Client v5.04 public beta release
Client v.5.04 is in public beta for Linux and Windows (console). It allows configuration of the amount of memory reported and the setting of advmethods through the Configuration so that it persists. This is a maintenance release, with more signficant improvements coming in v.6. See http://folding.stanford.edu/beta for more details.
2005年7月25日
v5.04公测版客户端发布
v.5.04 Linux和Windows(命令行)公厕版客户端发布。它允许通过Configuration选项设定内存报告数量和设置advmethods参数。这是测试版,带有v.6版中的一些改善功能。详见http://folding.stanford.edu/beta。
评分
- 7# vmzy
- 2005-8-2 23:32:28
7/26/2005 Planned network outtage, Thursday July 28, 2pm-5pm PDT We will have a planned network outtage on some of the FAH servers. It hopefully will not be too long. The stats update and stats cgi pages will also likely be down during this time. We may not get to all we need, so this outtage may be postponed to a later date, but we wanted to give a heads up. The data servers should not be affected, but one of the ASes will.
2005年7月25日
断网计划
7月28日星期四, 2pm-5pm PDT。我们将有一些FAH服务器计划性的断网。希望它不会太久。统计更新和统计cgi 页面在此期间可能会无法使用。我们可能不会很快如常所愿,因此这断网可能会持续很久,但我们想坚持到底。 数据服务器应该不会受影响,但一台AS除外。
2005年7月25日
断网计划
7月28日星期四, 2pm-5pm PDT。我们将有一些FAH服务器计划性的断网。希望它不会太久。统计更新和统计cgi 页面在此期间可能会无法使用。我们可能不会很快如常所愿,因此这断网可能会持续很久,但我们想坚持到底。 数据服务器应该不会受影响,但一台AS除外。
评分
- 8# vmzy
- 2005-8-5 00:06:00
8/3/2005
Folding@home researcher Chris Snow receives award at international conference for the second year in a row. Recent scientific results stemming from the Folding@home project garnered an award for "Best Poster" at the 19th Symposium of the Protein Society in Boston. This year's work from FAH centered around recent work on the ribosome, which is relevant both for fundamental biology (how proteins are synthesized, also known as "translation") as well as a better understanding of how many antibiotics work (roughly 50% of all antibiotics target the ribosome). This is the second Protein Society award for Snow and the third for FAH in general, which has won the award in three of the last 4 meetings.
2005年8月3日
Folding@home研究员Chris Snow在第二届国际会议中再次获得褒奖。Folding@home项目的最近科学研究结果获得了在波士顿举行第19届蛋白质联盟大会的一个"最佳成果"奖。今年FAH的工作集中在核糖体方向, 它不仅与基础生物学(蛋白质如何合成,亦称"转录")相关，并且能更好的理解抗生素运作原理(大约50%的抗生素依赖于核糖体)。这是蛋白质联盟颁给Snow的第二个奖，也是其颁给FAH的第三个奖,FAH在前4次大会中获得了三个奖。
Folding@home researcher Chris Snow receives award at international conference for the second year in a row. Recent scientific results stemming from the Folding@home project garnered an award for "Best Poster" at the 19th Symposium of the Protein Society in Boston. This year's work from FAH centered around recent work on the ribosome, which is relevant both for fundamental biology (how proteins are synthesized, also known as "translation") as well as a better understanding of how many antibiotics work (roughly 50% of all antibiotics target the ribosome). This is the second Protein Society award for Snow and the third for FAH in general, which has won the award in three of the last 4 meetings.
2005年8月3日
Folding@home研究员Chris Snow在第二届国际会议中再次获得褒奖。Folding@home项目的最近科学研究结果获得了在波士顿举行第19届蛋白质联盟大会的一个"最佳成果"奖。今年FAH的工作集中在核糖体方向, 它不仅与基础生物学(蛋白质如何合成,亦称"转录")相关，并且能更好的理解抗生素运作原理(大约50%的抗生素依赖于核糖体)。这是蛋白质联盟颁给Snow的第二个奖，也是其颁给FAH的第三个奖,FAH在前4次大会中获得了三个奖。
评分
- 9# vmzy
- 2005-8-12 22:30:56
8/11/2005 Updated stats system db
We've updated the stats system to handle large number of points much better.
2005年8月11日 更新统计系统数据库
我们已经更新了数据库系统，以更好的处理points的大数值越界问题。
We've updated the stats system to handle large number of points much better.
2005年8月11日 更新统计系统数据库
我们已经更新了数据库系统，以更好的处理points的大数值越界问题。
评分
- 10# vmzy
- 2005-8-16 23:01:16
8/15/2005 Stanford network issues.
The Stanford net is having major issues right now and is slow. Stanford IT knows about the issue and is on it. Hopefully there won't be much impact on FAH, although clients may need to retry more often until this is fixed.
2005年8月15日斯坦福网络故障
斯坦福的网络现在出了大问题，网速很慢。斯坦福的IT精英正在处理。希望不会对FAH产生太大的影响,不过在问题解决前，客户端可能需要多次连接才能成功。
The Stanford net is having major issues right now and is slow. Stanford IT knows about the issue and is on it. Hopefully there won't be much impact on FAH, although clients may need to retry more often until this is fixed.
2005年8月15日斯坦福网络故障
斯坦福的网络现在出了大问题，网速很慢。斯坦福的IT精英正在处理。希望不会对FAH产生太大的影响,不过在问题解决前，客户端可能需要多次连接才能成功。
评分
- 11# vmzy
- 2005-8-22 22:48:37
8/21/2005 Stats crediting.
We have develop a way to efficiently test to see whether a WU has been credited and are running a stats update with this tool. WUs which haven't been credited in the past for some issue will likely be credited in this upcoming pass. Since many checks must be made during this process, it's slow and may take 1-2 days to complete.
2005年8月21日 积分统计更新
我们已经开发了一种高效率地测试WU是否已打分的功能，我们马上进行统计更新，加入对此功能的支持。从前因为某些问题而未打分的WUs可能会尽快被打分。因为在此过程中需要进行许多检查,所以更新会很慢,也许需要1-2天完成。
We have develop a way to efficiently test to see whether a WU has been credited and are running a stats update with this tool. WUs which haven't been credited in the past for some issue will likely be credited in this upcoming pass. Since many checks must be made during this process, it's slow and may take 1-2 days to complete.
2005年8月21日 积分统计更新
我们已经开发了一种高效率地测试WU是否已打分的功能，我们马上进行统计更新，加入对此功能的支持。从前因为某些问题而未打分的WUs可能会尽快被打分。因为在此过程中需要进行许多检查,所以更新会很慢,也许需要1-2天完成。
评分
- 13# vmzy
- 2005-8-24 23:57:13
8/23/2005
We have been beefing up the FAQs, which can be found on our main FAQ page. What's especially new are FAQs on specific issues of interest to donors: configuration (esp for bonus point WUs), how the point system works, QMD, Gromacs, and others.
2005年8月23日
我们更新了FAQ页面,详见FAQ主页面。特别更新了FAQ中的志愿者比较感兴趣的部分:配置(特别是WU积分),积分系统运作原理, QMD, Gromacs等。
We have been beefing up the FAQs, which can be found on our main FAQ page. What's especially new are FAQs on specific issues of interest to donors: configuration (esp for bonus point WUs), how the point system works, QMD, Gromacs, and others.
2005年8月23日
我们更新了FAQ页面,详见FAQ主页面。特别更新了FAQ中的志愿者比较感兴趣的部分:配置(特别是WU积分),积分系统运作原理, QMD, Gromacs等。
评分
- 14# vmzy
- 2005-10-6 23:56:04
9/20/2005 FAH passes the 200,000 active CPU count
FAH's power continues to grow, now pushing beyond the 200,000 active CPU count.
2005年9月25日
FAH活跃CPU总数突破20万大关
FAH的实力继续增长，现活跃CPU总数已经超过20万。
FAH's power continues to grow, now pushing beyond the 200,000 active CPU count.
2005年9月25日
FAH活跃CPU总数突破20万大关
FAH的实力继续增长，现活跃CPU总数已经超过20万。